UC San Diego, ALTOS Lab
Reprogramming Aging: Science, Responsibility, and the Future of Healthy Longevity
Talk
Aging and disease are characterized by the functional decline of tissues and organs. Different interventions have been proposed to delay aging and the onset of age-associated decline and disease to extend healthspan. As disease and aging are associated with altered epigenetic mechanisms of gene regulation, such as DNA methylation, histone modification and chromatin remodelling, and non-coding RNAs, the manipulation of these mechanisms might be central to the effectiveness of treating disease as well as healtspan interventions. I will discuss some of the epigenetic changes that occur during disease and aging and how partial reprogramming by the Yamanaka factors might be a potential avenue to restore cell health and resilience through cellular rejuvenation programming to reverse disease, injury, and the disabilities that can occur throughout life.
Bio
Prominent Spanish scientist, currently a professor at the Salk Institute for Biological Studies in California, where he leads the Cell Biology Laboratory. His pioneering research focuses on aging and longevity, exploring fundamental biological mechanisms and developing advanced techniques such as cellular reprogramming. His work has opened new perspectives in regenerative medicine, aiming to improve quality of life and slow down aging processes. Izpisúa Belmonte is also a member of various international scientific committees, contributing to the progress of biological sciences globally.
He collaborates with global institutions to promote advancements in anti-aging medicine.
